Anthony DeSclafani will come off the 60-day injured list to make his first start since April 21 when the visiting San Francisco Giants try to stop the Atlanta Braves on Tuesday night in the second game of a four-game series.

The veteran right-hander has been out due to right-ankle inflammation and has missed 53 games. DeSclafani (0-1, 6.08 ERA) will face Atlanta rookie right-hander Spencer Strider (3-2, 2.45).

The Braves won the series opener 2-1 on Monday and have won 16 of their past 18 games. San Francisco has lost two in a row after winning seven of the previous eight.

DeSclafani made two rehab starts with Triple-A Sacramento and was give the approval to return after he threw 60 pitches in a start on June 16. He allowed four runs (three earned) in 5 2/3 combined innings. He joined the team in Atlanta and was officially named the starting pitcher following Monday’s game.

In his most recent major league appearance, DeSclafani took a loss against the New York Mets on April 21 when he allowed five runs on nine hits in five innings.

DeSclafani has made seven career starts against Atlanta, going 1-4 with a 4.54 ERA. He lost both of his starts against the Braves last year, most recently falling on Sept. 19, when he gave up two runs in six innings.

With the return of DeSclafani and Alex Cobb, who returned Sunday after missing 13 games with a neck strain, the Giants have their top five starters back in the rotation.

“I don’t think we’ve really had a stretch where the starting five have been pitching together,” Cobb said. “